Pharmacological and Pharmaceutical Sciences | Article | Published 2018

THE STUDY EMBRYOTOXICITY AND TERATOGENICITY MAIN ALKALOID ARUNDO DONAX DONAXINE

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Keywords: аrundo donax, donaksin, embryotoxicity, teratogenicity, the therapeutic dose, the maximum dose, implantation, organogenesis

Abstract

studied teratogenic and embryotoxic action Arundo donax grown in Uzbekistan. Studying embryotoxicity and teratogenicity main alkaloid Arundo donax Donaxina conducted on 60 female albinos rats, weighing 180.0 g and 160,0- fruit from mothers of newborns, administration of study drug. Doses of the test substance were calculated per unit body weight of the animal, using the maximum (200 mg / kg) and therapeutic (5 mg / kg). Research analyzes the main alkaloid Arundo donax Donaxine in doses of 5 mg/kg and 200 m g/kg when administered «per os» doses not possess teratogenic and embryotoxic.

References

  1. Саноев З.И., Якубова Л.К. ИССЛЕДОВАНИЕ ЭМБРИОТОКСИЧНОСТИ
  2. ТЕРАТОГЕННОСТИ ГЛАВНОГО АЛКАЛОИДА ARUNDO DONAX
  3. ДОНАКСИНА / Sanoev Z.I., Yakubovа L.K. THE STUDY EMBRYOTOXICITY
  4. TERATOGENICITY MAIN ALKALOID ARUNDO DONAX DONAXINE. Наука, техника и образование 2018. № 1 (42), p.51-55
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