Pharmacological and Pharmaceutical Sciences | Article | Published 2025

ACUTE TOXITY AND ANTICONVULSANT ACTIVITY OF 5-(P-AMINOPHENYL) - 4 - AMINO-1,2,4TRIAZOLE-3(2H)-THIONE

Authors:
Collection: EURASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES
Keywords: 5-(p-aminophenol)-4-amino- 1,2,4-triazole-3(2H)-thione, low-toxic, psychopharmacological activity, anticonvulsant activity, carbamazepine, convulex

Abstract

In this article, it has been experimentally confirmed that, 5- (p-aminophenyl)-4-amino-1,2,4-triazole-3(2H)-thione belongs to the class of low-toxic psychopharmacological activity in doses of 0.1; 0.5; 1.0; 5.0 and 10.0 mg/kg and is not inferior to comparable anticonvulsant drugs carbamazepine and convulex.

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