Bioengineering and Life Sciences | Article | Published 2019
Small RNAs (sRNAs) are short, non-coding, 17–24 nucleotides long RNA molecules that play vital roles in regulating gene expression in every known organism investigated to date including cotton (Gossypium ssp.). These tiny RNA molecules target diverse categories of genes from diﬀerent biological and metabolic processes and have been reported in the three domains of life. Small RNAs, including miRNAs, are involved in ovule and ﬁber development, biotic and abiotic stresses, fertility, and other biochemical processes in cotton species. Also, sRNAs are the critical components in RNA interference pathway. In this article, we have reviewed the research eﬀorts related to the isolation and characterization of miRNAs using molecular and genomic approaches. The progress made in understanding the functional roles of miRNAs in regulation, alteration, and inactivation of fundamental plant processes and traits of importance in cotton are presented here.
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