Medical and Health Sciences | Article | Published 2011
Purpose: study of the process of reparative regeneration of long bones in case of a local use of a natural mineral (white marble) in an experiment on rats. Methods: a comparative experimental-morphological study of the effect, produced by calcium-containing materials on activation of reparative osteogenesis, was conducted on 60 nonpedigreed white rats. Preparations were implanted into a diaphyseal defect of the femur; the material was studied on days 7, 14, 21, 30 and 60 after the operation. Results: it was found out that all tested materials facilitated formation of a neogenic bone on their surface; the most evident activation of reparative osteogenesis was observed after implantation of marble powder, a less degree was caused by calcium carbonate. Conclusion: marble powder implants are biocompatible, have osteoconductive properties and can be recom mended for use in orthopaedic surgery for repairing bone tissue defects