Biomedical and Biological Engineering | Article | Published 2022

Involvement of sphingolipids in the cell metabolism and various pathologies

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Keywords: sphingolipids, sphingomyelin, ceramide, sphingosine, acid sphingomyelinase, neutral sphingomyelinase, oxidative stress, cytokines, neurodegeneration

Abstract

Being an essential component of plasma membrane, sphingolipids are bioactive lipids playing key roles in regulation of signaling. Compositions of sphingolipids, sphingolipid metabolism and its regulation in tissues, as well as involvement of sphingolipids in various pathological processes are analyzed in the review.

References

  1. Being an essential component of plasma membrane, sphingolipids are
  2. bioactive lipids playing key roles in regulation of signaling. Compositions of
  3. sphingolipids, sphingolipid metabolism and its regulation in tissues, as well as
  4. involvement of sphingolipids in various pathological processes are analyzed in the
  5. review.
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