Medical and Health Sciences | Article | Published 2023
Preeclampsia, according to the World Health Organization, complicates pregnancy in 8-26% of cases and is one of the main causes of maternal and perinatal mortality. The purpose of the study was to evaluate the prognostic significance of the biochemical markers homocysteine, lactate dehydrogenase(LDH), reactive protein C and vitamin D using ROC analysis in preeclampsia of varying degrees. Material and methods. A prospective study included 105 patients with preeclampsia and 31 physiologically ongoing pregnancies. A general clinical and laboratory examination of pregnant women was carried out. Results. The results of the study and according to the ROC curve showed a high value of LDH determination (AUC=0.97) (sensitivity=95.9%; specificity=93.5%). and C-reactive protein(CRP) (AUC=0.96) (sensitivity=97.3%; specificity=96.8%) in the diagnosis of the disease. 77.2%). Conclusion. The developed model for predicting preeclampsia can be used in the work of a practicing obstetrician-gynecologist